Dyadic International (NASDAQ:DYAI) vs. Aligos Therapeutics (NASDAQ:ALGS) Head-To-Head Contrast

Dyadic International (NASDAQ:DYAIGet Rating) and Aligos Therapeutics (NASDAQ:ALGSGet Rating) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, earnings, risk, profitability, analyst recommendations, institutional ownership and valuation.

Analyst Recommendations

This is a breakdown of current recommendations and price targets for Dyadic International and Aligos Therapeutics, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Dyadic International 0 1 1 0 2.50
Aligos Therapeutics 0 5 0 0 2.00

Dyadic International presently has a consensus price target of $6.00, suggesting a potential upside of 209.28%. Aligos Therapeutics has a consensus price target of $7.00, suggesting a potential upside of 503.45%. Given Aligos Therapeutics’ higher possible upside, analysts plainly believe Aligos Therapeutics is more favorable than Dyadic International.

Institutional & Insider Ownership

13.5% of Dyadic International shares are owned by institutional investors. Comparatively, 70.1% of Aligos Therapeutics shares are owned by institutional investors. 27.0% of Dyadic International shares are owned by company insiders. Comparatively, 14.8% of Aligos Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Volatility and Risk

Dyadic International has a beta of 0.25, suggesting that its share price is 75% less volatile than the S&P 500. Comparatively, Aligos Therapeutics has a beta of 2.39, suggesting that its share price is 139% more volatile than the S&P 500.


This table compares Dyadic International and Aligos Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Dyadic International -506.23% -66.67% -57.88%
Aligos Therapeutics -1,547.22% -73.09% -56.71%

Earnings & Valuation

This table compares Dyadic International and Aligos Therapeutics’ gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Dyadic International $2.40 million 22.98 -$13.07 million ($0.42) -4.62
Aligos Therapeutics $4.36 million 11.39 -$128.33 million ($2.98) -0.39

Dyadic International has higher earnings, but lower revenue than Aligos Therapeutics. Dyadic International is trading at a lower price-to-earnings ratio than Aligos Therapeutics, indicating that it is currently the more affordable of the two stocks.


Dyadic International beats Aligos Therapeutics on 8 of the 14 factors compared between the two stocks.

About Dyadic International

(Get Rating)

Dyadic International, Inc., a biotechnology platform company, develops, produces, and sells enzymes and other proteins in the United States. The company utilizes its patented and proprietary C1 platform and other technologies to conduct research, development, and commercial activities for the development and manufacturing of human and animal vaccines and drugs, such as virus like particles and antigens, monoclonal antibodies, bi/tri-specific antibodies, fab antibody fragments, Fc-fusion proteins, biosimilars and/or biobetters, and other therapeutic enzymes and proteins. It offers DYAI-100, SARS-CoV-2-RBD antigen vaccine candidate towards a first-in-human Phase 1 clinical trial, is to validate to serve as proof of concept for the development of next generation multivariant COVID-19 vaccine candidates. The company has a research and development agreement with VTT Technical Research Centre of Finland, Ltd.; strategic research services agreement with Biotechnology Developments for Industry in Pharmaceuticals, S.L.U.; and collaboration with Syngene International Limited. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.

About Aligos Therapeutics

(Get Rating)

Aligos Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses to develop novel therapeutics to address unmet medical needs in viral and liver diseases. Its lead drug candidate is ALG-010133, a s-antigen transport-inhibiting oligonucleotide polymer that is in Phase Ib clinical trial for the treatment of chronic hepatitis B (CHB); and ALG-000184, a capsid assembly modulator, which is in Phase I clinical trials to treat CHB. The company also develops ALG-020572, an antisense oligonucleotide to prevent HBsAg translation and secretion; and ALG-055009, a small molecule THR-ß agonist that is in the Phase 1a/1b for the treatment of non-alcoholic steatohepatitis(NASH). In addition, it develops siRNA drug candidate, ALG-125755, as well as ALG-125097 and ALG-125819, demonstrated potent inhibition of HBsAg release from HBV-infected cells. It has entered into license and collaboration agreements with Luxna Biotech Co., Ltd. to develop and commercialize products containing oligonucleotides targeting hepatitis B virus genome; Emory University to provide hepatitis B virus capsid assembly modulator technology; research, licensing, and commercialization agreement with Katholieke Universiteit Leuven to develop coronavirus protease inhibitors; and Merck to discover, research, optimize, and develop oligonucleotides directed against a NASH. The company was incorporated in 2018 and is headquartered in South San Francisco, California.

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